@article{Avdosieva_Kalinina_Chaikovska_2020, title={BIRD FLU – COUNTER-STRATEGY}, volume={21}, url={https://scivp-journal.com.ua/index.php/journal/article/view/76}, DOI={10.36359/scivp.2020-21-1.01}, abstractNote={<p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The rapid growth of international cooperative ties poses a serious threat to the spread and spread of one of the few yet the most dangerous infections on the territory of Ukraine – bird flu. In addition to the economic damage caused by this disease to the poultry industry, an important aspect is the danger to human health and the potential risks of a new pandemic variant of the virus. The epizootic situation of this disease remains complex recently and cases are reported in most developed poultry countries</p> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The article provides analytical material on HPBF outbreaks in 2018-2019. In 2018 the HPBF was registered in 39 countries and outbreaks ranged from 1 to 110 and the highest in Taiwan were – 110, Russia – 82, Egypt – 49, Bulgaria – 29. In 2019 HPBF outbreaks were registered in 19 countries and ranged within from 1 to 107 and the highest number was in Taiwan – 107, Mexico – 35.</p> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; At present, there is a very difficult epizootic situation in the world for flu viruses caused by the following subtypes: H5N1, H5N2, H5N3, H5N5, H5N8, H5N9.</p> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; &nbsp;During 2018 registered strains of HPBF in the countries of the world were: N5 – 22; H5N1 – 16; H5N2 – 25; H5N3 – 2; H5N5 – 0; H5N6 – 8; H5N8 – 26; H5N9 – 1. During 2019, registered strains of HSVP in the countries of the world were harboring: N5 – 1; H5N1 – 10; H5N2 – 48; H5N3 – 17; H5N5 – 3; H5N6 – 4; H5N8 – 16; H5N9 – 0 %.</p> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; With regard to low pathogenic avian influenza (LPBF), their worldwide wide circulation in the natural reservoir has been proven to date. In 2019 the highest number of LPBF outbreaks caused by different strains was: H5N1 – 36; H7N3 – 29 and H5N2 – 22. During 2019, the reported LPBF strains in the countries were: H5 – 6; H5N1 – 34; H5N2 – 21.1; H5N5 – 0; H5N6 – 4; H5N8 – 0; H7N3 –; H7N4 – 3; H7N9 – 1; H7N5 – 2; H7N6 – 1 %.</p> <p>&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The use of the following antiviral medications for the prevention and treatment of LPBF revealed their high therapeutic and prophylactic significance, namely: remantadine, amizone, aminocaproic acid and made on the basis of modern nanotechnologies – Germacap. Due to the 2-time (with an interval of 7 days) use of remantadine aerosol for prevention of LPBF epizootic among ducklings, the conservation of livestock reached 93 %, whereas in control – only 37 %. When treated with remantadine, the young growth of egg crosses for therapeutic purposes resulted in a 45 % reduction in the discharge of livestock against control by reducing death and culling.</p&gt;}, number={1}, journal={Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology}, author={Avdosieva, I. K. and Kalinina, O. S. and Chaikovska, O. I.}, year={2020}, month={Jun.}, pages={11-22} }