@article{Garkavenko_Kozytska_Gorbatyuk_Kovalenko_2019, title={Study of stability of polyantibioticorezistan radius S. AUREUS to disinfectives with different active substances }, volume={20}, url={https://scivp-journal.com.ua/index.php/journal/article/view/25}, DOI={10.36359/scivp.2019-20-2.24}, abstractNote={<p>S. aureus is one of the main antibiotic-resistant pathogens of bacterial origin, which adapts very quickly to the selective pressure of antibiotic, antiseptic and disinfectants. It is believed that increased stability of staphylococci to antimicrobial agents is associated with uncontrolled application of them in the human population, in the population of animals, the spread of resistant strains between humans and animals, or the transfer of resistant strains from animals to humans (or vice versa) through direct contact and through consumption livestock industry products. <br>Consequently, the study of phenotypic and genotypic mechanisms for the formation of acquired resistance to antimicrobial agents and the search for their common genetic mechanisms for such anxiety are topical issues of the present.<br>The article presents research materials to determine the sensitivity of S. aureus field isolates to antibiotics and establishes the level of their resistance to all the drugs used. Based on the data presented, the polyantibiotic resistance of strains of Staphylococcus aureus with a resistance level of 11.1 to 88.9% was detected for 18 types of antibiotics used, including 3 strains of MRSA. The materials of the article give data on studies on the effects of some disinfectants on the polyantibiotic resin strain of the pathogen. The article presents the facts that revealed MRSA strains showed particular resistance to experimental disinfectants at certain working concentrations that did not neutralize the pathogen. Detected MRSA strains showed resistance to most antibiotics and were resistant to certain concentrations of disinfectants, which is probably due to the formation of a common phenotypic mechanism of resistance to the action of antibacterial drugs and agents.</p&gt;}, number={2}, journal={Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology}, author={Garkavenko, T. A. and Kozytska, T. G. and Gorbatyuk, O. I. and Kovalenko, V. L.}, year={2019}, month={Sep.}, pages={183-193} }