APPLICATION OF FEED ADDITIVE BAFASAL IN POULTRY
Todays is not possible to overcam the problem of the resistance of microorganisms to antibiotics by the development of new antimicrobial agents. Because the new drugs development is quite long process, and the addiction of microorganisms to the antibiotics occurs very fast, in resulting microorganisms become resistant. Prospective direction in solving the problem of antibiotic resistance is the use of bacteriophages, which lytically acting on the pathogens, not causing any toxic effect on the macroorganism.
In the article highlight the use of the feed additive Bafasal, which was made on the basis of a specific bacteriophage to serovars of Salmonella, in particular S. enteritidis, S. typhi, S. paratyphi, S. typhimurium, S. branderburg, S. hadar. Poultry of the experimental group were used Bafasal from 1 to 14 days of the experiment, from the calculation on 10 chickens - 50 cm3 of feed additive dissolved to 0,5 % concentration, and from 15 to 35 days - 100 cm3 of Bafasal dissolved to 0,25 % concentration. As a result in the conducted researches was found out that Bafasal causes an increase of weight gain of broilers, feed conversion. In particular, on the 35th day of the experiment, the average daily weight gain of the chickens of the experimental group was on 4,5 % higher than in broilers of the control group, and the conversion of feed in the experimental and control chicken was 1.74 and 1.93 units, respectively. Herewith, in broilers of the control group were not isolated pathogenic microorganisms, including salmonella. In determining the influence of the feed additive on some representatives of the intestinal flora of broilers was found that, the use of feed additive didnt cause changes in total amount lactic acid and bifidobacteria, in broiler of test and control groups, in the glandular, muscular stomach, duodenum, cecum and colon.
Abedon, Stephen T., Kuhl, Sarah J., Blasdcl, Bob G., Kutter, Elizabeth Martin (2011). Phage treatment of human infections. Bacteriophage,V. 1, Issue 2, 66-85.
Akimkin, V.G., Darbeeva, O.S., Kolkov, V.F. (2010). Bakteriofagi: istoricheskie i sovremennye aspekty ih primenenija: opyt i perspektivy. Klinicheskaja praktika, 4, 48-54 [in Russian].
Еreshсhenko, O.A., Strel'nikov, L.S., Tkachova, O.V., Tkach M.M. (2010). Doslіdzhennja gostroї toksichnostі pіni medichnoї z kompleksom bakterіofagіv. Aktual'nі pitannja farmacevtichnoї і medichnoї nauki ta praktiki, Vipusk XXIII, 4. 23-24 [in Ukrainian].
Inal, J.M. (2003). Phage Therapy: a Reappraisal of Bacteriophages as Antibiotics. Archivum Immunologiae et Therapiae Experimentalis, 51, 237–244.
Shevchenko, T.M., Voronkova, O.S., Vіnnіkov, A.І. (2014). Harakteristika chutlivostі do antibіotikіv ta fagіv shtamіv stafіlokokіv, shho vidіlenі z reproduktivnogo traktu mishe. Patologіja, 3 (32), 68‒72 [in Ukrainian].
Skurnik, M., Strauch, E. (2006). Phage therapy: Facts and fiction. International Journal of Medical Microbiology, 296, 5‒14.
Vorobej, Е., Voronkova, O., Sіrokvasha, O., Vіnnіkov, A. (2014). Lіkuval'no-profіlaktichnі preparati bakterіofagіv. Vіsnik L'vіvs'kogo unіversitetu. Serіja bіologіchna, 64, 52-66 [in Ukrainian].
This work is licensed under a Creative Commons Attribution 4.0 International License.