Efficiency of the technological feed additive Hepasorbex concerning some micotoxins
It was conducted research under laboratory conditions, concerning the effectiveness of the technological feed additive Hepasorbeks, which belongs to the functional group of substances that reduce the feed contamination by mycotoxins. The objective of our research was to establish in vitro the effectiveness of the feed additive Hepasorbeks by confirming its ability to restrain or reduce the absorption of mycotoxins (fumonisins and T2 toxin). The effectiveness of the specific action of the feed additive was determined quantitatively at various pH values, simulating a change in the acidity of the medium in the digestive canal of animals. The research was conducted in two stages: screening - using solution of mycotoxin and the main - using compound feed, which contained mycotoxins. At the screening stage, feed additive Hepasorbeks was added to buffer solutions containing, respectively, fumonisins and T2-toxin in an amount of 200 mcg/g. In the main experiment, the feed additive Hepasorbeks was added to the compound feed at the rate of 1, 2, 5 g / kg and the samples were thoroughly homogenized. The absorption magnitude (in an acidic medium) and the desorption magnitude (in an alkaline medium) were determined. The criterion for evaluating the effectiveness was the practical coefficient of efficiency, which was calculated by determining the difference between the amount of inserted mycotoxin and the amount of mycotoxin adsorbed after incubation in an acidic medium, taking into account the value of desorption after incubation in an alkaline medium. It was established that during screening studies, the practical coefficient of efficiency of the feed additive relative to fumonisins was 78,0%, and relative to T2 toxin was 70.5%. In the main experiment, it was found that the practical coefficient of efficiency of the feed additive depending on the dose was 69,1 – 72,3% for fumonisins and 38,2 - 41,6% for T2 toxin. The findings of investigation confirm that the feed additive Hepasorbeks evinces marked adsorption properties to fumonisins and T2-toxins.
Commission Regulation (EC) № 429/2008 of 25 April 2008 on detailed rules for the implementation of Regulation (EC) No 1831/2003 of the European Parliament and of the Council as regards the preparation and the presentation of applications and the assessment and the authorisation of feed additives (Official Journal of the European Union L 133, 22.5.2008. — Р. 60).
Fruhaufa S. Yeast cell based feed additives: studies on aflatoxin B1 and zearalenone /Sebastian Fruhaufa, Heidi Schwartza, Franz Ottner, Rudolf Krska and Elisavet Vekiru // Food Additives and Contaminants, Vol. 29, No. 2, February 2012, 217–231.
Golovnja E. Nuzhno li ocenivat' jeffektivnost' sorbentov / Kombikorma, №4, 2014, s.67-68. (in Russian)
Kocyumbas I.Ya. Klinichni doslidzhennya vetery`narny`x preparativ ta kormovy`x dobavok/ I.Ya. Kocyumbas, I.Yu.Bisyuk, V.M.Gorzheyev, O.G.Maly`k ta in.. Za red. d-ra vet. nauk, prof. I.Ya. Kocyumbasa L`viv, 2013 – 252 s. (in Ukrainian)
Levytskyi T. R. Efektyvnist zastosuvannia tekhnolohichnoi kormovoi dobavky. Naukovyi visnyk LNUVMMBT im. S.Z.Hzhytskoho, Seriia "Veterynarni nauky", Tom 20 № 84. 2018. S. 142-147. (in Ukrainian).
Lysko S. B. Sorbcionnaja aktivnost' novogo sorbenta prirodnogo proishozhdenija v otnoshenii T-2 toksina./ Veterinarija i kormlenie. 2013, № 6, s.28-29. ( in Russian)
Malkov M.A., Bogomolov V.V., Dan'kova T.V., Krasnov K.A. Mikotoksiny – strategija ustranenija ih vlijanija na organizm sel'skohozjajstvennyh zhivotnyh i pticy / Cenovik, № 1, 2012, s.74-75( in Russian)
Vekiru E. Investigation of various adsorbents for their ability to bind Aflatoxin B1 / E. Vekiru, S. Fruhauf, M. Sahin, F. Ottner, G. Schatzmayr, R. Krska//Mycotoxin Research Vol. 23, No. 1 (2007), 27-33.
Zakon Ukrayiny` «Pro bezpeku ta gigiyenu kormiv», Golos Ukrayiny`, № 12, 19.01.2018 (in Ukrainian).
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