A new mineral drug for veterinary practice “Calfomin”

  • R. M. Sachuk Research Epizootology Station IVM NAAS, Rivne, Ukraine
  • S. V. Zhyhalyuk Research Epizootology Station IVM NAAS, Rivne, Ukraine
  • Ya. S. Stravsky Ternopil State Medical University named after Gorbachevsky Ministry of Health of Ukraine, Ternopilʹ, Ukraine
  • A. I. Chaykovska State Scientific-Research Control Institute for Veterinary Medicinal Products and Feed Additives, Lviv, Ukraine
  • O. A. Katsaraba Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies, Lviv, Ukraine
  • N. P. Boltyk Ternopil Research Station, Institute of Veterinary Medicine, NAAN, Ternopil, Ukraine
Keywords: oral preparation, minerals, amino acids, “Calfomine”, postpartum paresis

Abstract

A new pharmaceutical composition “Calfоmin”, that includes macro-and trace elements in the form of water-soluble salts, namely Calcium, Phosphorus, Magnesium, Natrium, Potassium, Ferum, Mangan, Zinc, Cobalt and Kuprom, is presented in the article. Also drug include essential amino acids - methionine and lysine. The drug is used for the treatment and prevention of diseases of cows, pigs, sheep and goats, associated with metabolic disorders of the listed nutrients (postpartum paresis, rachitis in young animals, osteomalacia in the elderly animals). The drug is effective in allergies, toxicosis, postpartum hemoglobinuria, spotted disease, hives, exanthema, hemorrhagic diathesis, hematuria and myoglobinuria; paresis due to a deficit of Calcium or Phosphorus of different etiology. “Calfоmin» is recommended as an auxiliary therapy for Poisoning with Lead, Fluorine or Acidic Acid, and for poultry to improve egg-laying. The drug is used to increase the weight gain of animals on fattening, etc. 

When administered to laboratory animals in the stomach, intraperitoneally and subcutaneously, it is established that the drug belongs to the IV class toxicity according to the GCM 85.2-37-736: 2011 and GOST 12.1.007-76, that is, it belongs to low-toxic substances. The data on the significant increase in Calcium, inorganic Phosphorus, Zinc and Kuprum in the serum of domesticated cows, which were orally called “Calfоmin”, were obtained on the 3rd day. And on the 14th day the activity of these elements was already within the limits of physiological norms. Oral administration to cows “Calfоmin” in a dose of 30 ml per 100 kg of body weight for 10 days after a calving prevents postpartum paresis. “Calfоmin” is of interest to veterinary medicine, and therefore it is expedient to continue its further clinical study and standardize the indicators of its quality.

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Published
2019-09-18
How to Cite
Sachuk, R. M., Zhyhalyuk, S. V., Stravsky, Y. S., Chaykovska, A. I., Katsaraba, O. A., & Boltyk, N. P. (2019). A new mineral drug for veterinary practice “Calfomin”. Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology, 20(2), 390-399. https://doi.org/10.36359/scivp.2019-20-2.50