Comparative evaluation of fipronil based preparations for invasions of dogs and cots with ecoparazites
The article presents data on the effectiveness of the new domestic anti-parasitic drug "Profile spot for dogs and cats (drops for external use)" compared to the drug "Insectostope for dogs and cats (liquid of the skin)" (active ingredient of drugs fipronil) in dogs and cats of different breeds in the use of them with a preventive and curative purpose for ectoparasit invasions. Extensiveness of invasion (EI) was defined as the ratio of the number of infected animals to the number of selected, expressed in percents. The intensity of invasion (II) with fleas and lice was determined by counting ectoparasites at 10 cm² of the skin of the animal's skin, and ticks by the number of individuals per animal. Extensive efficacy (EЕ) of the preparation was calculated based on the number of treated animals in percentages, which were completely exempt from parasites. According to the results of the conducted researches, stable invasion of all 17 dogs and 15 cats fleas involved in the study was established. In 14 dogs and 8 cats, a mixed invasion of fleas and lice and 7 dogs and 4 cats was revealed, along with mixed infestation, skin lesions and Ixodes ricinus mites were detected. At the same time, the intensity of invasion in dogs and cats by fleas ranged from 5 to 8 individuals and lice from 1 to 3 individuals per 10 cm² of animal skin area, and the ticks infestation was 2-7 individuals per animal's body. The experimental and control groups of animals were dosed individually, once. In doses according to leaflets tabs. At 2, 5, 7 days after treatment, dead animals, lice and mites were found on treated animals, and 10 and 30 days of ectoparasites on the animal's body were not detected. During the treatment of complications or changes in clinical condition, no extraneous efficacy (EE) of preparations for manufacturing tests for the defeat of dogs and cats by fleas, lice and ticks was 100 %.
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