The influence of citrate I, Se, S on the hematological profile and body weight dynamics of broiler chickens in the presence and absence of coccidiostatics in the mixed feed

  • U. I. Tesarivskaya State Scientific Research Control Institute of Veterinary Medicinal Products and Feed Additives, Lviv, Ukraine
  • R. S. Fedoruk Institute of Animal Biology of NAAS, Lviv, Ukraine
  • O. I. Koleschuk Institute of Animal Biology of NAAS, Lviv, Ukraine
  • S. Ya. Martynyk State Scientific Research Control Institute of Veterinary Medicinal Products and Feed Additives, Lviv, Ukraine
  • O. M. Maksymovych State Scientific Research Control Institute of Veterinary Medicinal Products and Feed Additives, Lviv, Ukraine
Keywords: chicken broilers, hematological profile, dynamics of body weight, biological action, citrate I, Se, S

Abstract

The results of the influence of different doses of I, Se, S citrate, synthesized by the method of nanotechnology on the body of chicken broilers with the presence and absence of the coccidiostatic «Coccisan» in the feed are given. The drinking with water of 5, 10, 20, 30, 40 μg I / L when introduced into the mixed fodder coccidiostatic probably did not affect the number of red blood cells, leukocytes and their forms, the content of hemoglobin in the blood of 35 days of growth and development compared with the control of poultry in the control group, except for the hematocrit, which was chicken in the action of 40 μg I / L was lower than in the control. The number of leukocytes and leukogram in the blood of chickens in experimental groups was not significantly different from those in the poultry of the control group. Analysis of changes in morphological parameters of blood during the technological period of slaughter of chicks on the 48th day of growth and development and exclusion from the finishing mixed fodder «Coccisan» indicates the probable increase in the number of red blood cells in chickens in the blood of 20; 30 and 40 μg I / L, hemoglobin content at the action of 20 and 40 μg I / L, hematocrit values at the action of 5 and 40 μg I / L compared to the control group chickens. The lower level of leukocytes is noted for the actions of 20 and 30 μg I / L. An analysis of blood chicken leukograms indicates a higher relative lymphocyte level in the blood of chickens at 10 μg I / L, but decreasing it by action of 20 μg I / L and 30 μg I / L. Characteristically, a decrease in the relative level of lymphocytes in the blood of chickens at the action of 40 μg I / L was noted with an increase in the level of pseudoiesinophils.

Investigation of the body weight of chicken broilers indicates that the introduction of I, Se, S citrate contributed to the increase in the intensity of growth of all experimental poultry species in the first 7 days, except for the actions of 30 μg I / L. At 21 - 28 days of cultivation, there is no probable decrease in the body weight index of chickens in all experimental groups. The lowest body weight of chickens for 14 - 35 days of growth is set at the action of 20 μg I / L. Excretion of «Coccisan» from mixed fodder contributed to an increase in the intensity of their growth of chickens during subsequent periods (42 and 48 days) in experimental groups compared with the control group. A more pronounced productive effect at 42 and 48 days is found in chickens at the action of 10 μg I / L and 40 μg I / L.

References

WHO, UNICEF, and ICCIDD. Assessment of the Iodine Deficiency Disorders and monitoring their elimination. — Geneva: WHO, WHO/Euro/NUT, 2001. — P. 1–107.

WHO, UNICEF, and ICCIDD. Assessment of the Iodine Deficiency Disorders and monitoring their elimination. Third edition. — Geneva: WHO, WHO/Euro/NUT, 2007. — P. 1–98.

Zimmermann M. B. Iodine Deficiency / M. B. Zimmermann // Endocrine Reviews. — 2009. — Vol. 30 (4). — P. 376–408.

Zimmermann M. B. Iodine-deficiency disorders / M. B. Zimmermann, P. L. Jooste, C. S. Pandav // Lancet. — 2008. — Vol. 372 (9645). — P. 1251–1262.

Perederiy V. H. Osnovy vnutrishnʹoyi medytsyny / V. H. Perederiy, S. M. Tkach - Vinnytsya: Nova Knyha, 2009. - T. 1, 639 s. (in Ukrainian)

Pedraza P. E. Mechanisms of adaptation to iodine deficiency in rats: Thyroid status is tissue specific. Its relevance for man / P. E. Pedraza, M. J. Obregon, H. F. Escobar-Morreale, del F. E. Rey, de G. M. Escobar, M. J. Obregon, H. F. Escobar-Morreale, del F. E. Rey, de G. M. Escobar // Endocrinology. — 2006, — P. 2098–2108

Bernal J. Thyroid hormones and brain development / J. Bernal // Vitam. Horm. — 2005, — P. 95–122.

Manzano J. Influence of thyroid hormones on maturation of rat cerebellar astrocytes / J. Manzano, J. Bernal, B. Morte // Int. J. Dev. Neurosci. — 2007, — P.171–179.

Köhrl J. Selenium in biology: facts and medical perspectives / J. Köhrl, R. Brigelius-Flohe, A. Böck, et al. // Biol. Chem. – 2000. – Vol. 381, № 9-10. – P. 849-864.

Baraboy V. A. Selen: biolohichna rolʹ i antyoksydantna aktyvnistʹ / V. A. Baraboy, E. N. Shestakova // Ukr. biokhim. zhurn. - 2004. - T. 76, № 1.– S. 23-32.11.

Beckett, G. J. Selenium and endocrine systems. / G. J. Beckett, J. R. Arthur // J. Endocrinol, – 2005. –, Vol.184. – I.3. – Р.455 – 465 .

Poyednanyy defitsyt yodu i sela ta yoho vplyv na perebih vahitnosti / A. YU. Lymansʹka, YU. V. Davydova, O. M. Mokryk, L. M. Bulyk // Visnyk problem biolohiyi i medytsyny - 2016 - Vyp. 2, Tom 3 (130). 52– 56. (in Ukrainian)

Schomburg L. On the importance of selenium and iodine metabolism for thyroid hormone biosynthesis / L. Schomburg, J. Köhrle // Mol. Nutr. Food Res. – 2008. –, Vol.52. – I.11. – Р. 1235 – 1246

Oberlis D. The biological role of macro- and micronutrients in humans and animals / D. Oberlis, B. Garland., A. Skalny // SPb. The science. – 2008. – 542 p.

Migues P. V. Dehydroepiandrosterone and its sulphate enhance memory retention in day-old chicks / P. V. Migues, A. N. B. Johnsto, S. P. R Rose // Neurosci. – 2002 –Vol. 109, I.2. — P. 243 – 251.

Commission Regulation (EC) No 1459/2005 of 8 Sept. 2005 amending the conditions for authorisation of a number of feed additives belonging to the group of trace elements. Official Journal of the European Union L233. — 2005 — P. 8–10

Herzig I. Utilisation of iodine from different sources in pigs / I. Herzig, B. Pisaikova, J. Kursa, P. Suchy // Arch Tierernahr. – 2000. – Vol. 53, N 2. – P. 179–189.

Antonyak H. L. Biokhimichna ta heokhimichna rolʹ yodu: monohrafiya. L. Antonyak, V. V. Vlizlo // LNU im. Ivana Franka, 2013. - 392 s. (in Ukrainian)

Artelt H. M. Selenium in Swine Nutrition / H. M. Artelt // RETORTE Ulrich Scharrer GmbH, Germany. –Vol. 10. – 2001. – Р. 112-119.

Surai P. F. Is Organic selenium letter fjr animals than inorganic sources / P. F. Surai, J. E. Dvorska // Feed Mix. –2001. – Vol. 9. – Р. 8-10.

Antyoksydantnyy status orhanizmu kurey v krytychni periody i rozvytku dlya dodatkovoho vykorystannya mineralʹnoyi dobavky do ratsioniv / YA. M. Sirko, B. YA. Kyryliv, V. O. Kystsiv, ta in. // Nauk.-tekhn. byul. In-tu biolohiyi tvaryn ta DNDKI vetpreparativ ta korm. dobavok. - 2014. - Vyp. 15, N 1. - S. 77-83. (in Ukrainian)

Lesyk YA. V. Rezystentnistʹ orhanizmu kroliv ta dynamiky masy tila krovi dlya umov reyestratsiyi spoluk khromu (III) ta sulʹfatu natriyu / YA. V. Lesyk, R. S. Fedoruk, O. P. Dolaychuk // Biolohiya tvaryn. - 2014. - 16, № 3. - S. 76-84. (in Ukrainian)

Tesarivsʹka U. I. Metabolichna ta toksychna diya riznykh doz «nanotsytrativ» I, Se, S v orhanizmi laboratornykh shchuriv / U. I. Tesarivsʹka, R. S. Fedoruk, V. H. Kaplunenko, ta in. // Visnyk Sumsʹkoho natsionalʹnoho ahrarnoho universytetu. - 2018. —№ 1 (42). - s. 220 - 224. (in Ukrainian)

European convention for the protection of vertebrate animals used for experim. and other scientific purposes. Coun. of Europe, Strasbourg. 1986. pp. 53.

Vlizlo V. V. Laboratorni metody doslidzhennya v biolohiyi, tvarynnytstvi ta veterynarniy medytsyni: dovidnyk / V. V. Vlizlo, R. S. Fedoruk, I. B. Ratych, ta in.; za red. V. V. Vlizla. - Lʹviv: SPOLOM, 2012. - 764 s. (in Ukrainian)

Published
2019-09-18
How to Cite
Tesarivskaya, U. I., Fedoruk, R. S., Koleschuk, O. I., Martynyk, S. Y., & Maksymovych, O. M. (2019). The influence of citrate I, Se, S on the hematological profile and body weight dynamics of broiler chickens in the presence and absence of coccidiostatics in the mixed feed. Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology, 20(2), 24-33. https://doi.org/10.36359/scivp.2019-20-2.03