Effective innovations prevention newcastle disease

  • I. K. Avdosieva State Scientific Research Control Institute of Veterinary Medicinal Products and Feed Additives, Lviv, Ukraine
  • O. B. Basarab State Scientific Research Control Institute of Veterinary Medicinal Products and Feed Additives, Lviv, Ukraine
  • V. V. Reghenchuk State Scientific Research Control Institute of Veterinary Medicinal Products and Feed Additives, Lviv, Ukraine
  • I. L. Melnychuk State Scientific Research Control Institute of Veterinary Medicinal Products and Feed Additives, Lviv, Ukraine
Keywords: newcastl disease, vector vaccines, HVT-NDV VECTORMUNES, hemaglutnation delay react, ELISA (IDVet, France)

Abstract

The article presents the comparative evaluation of two methods of serologic control of the effectiveness of broiler vaccination with VECTORMUN HVT-NDV vaccine against Newcastle disease (NH). It has been established that both methods, such as ELISA (test system of the company IDvet, France), and RZGA are sensitive and detect protective antibodies to the NH virus in serum broilers. Single vaccine incubation with vector vaccine VECTORMUN HVT-NDV vs. NH is absolutely sufficient for the formation and establishment of a stable immunity against NH, reduces the stress effect compared to mass vaccination in the poultry manure.

With the use of a vector vaccine there is no horizontal distribution of the vaccine virus: the risk of contamination of the environment with pathogens of viral diseases is excluded, which may lead to uncontrolled infection of the bird.

The use of the vector vaccine provides a stable epizootic situation in the farm: it does not cause post-vaccination reactions, the spread of the vaccine virus ("rolling disease"), increases the immune status of the herd, thereby reducing the negative impact of viral and bacterial agents on the body of the bird during the growing season and the number of bird vaccinations, causes prolonged immunity, therefore, as a rule, there is no need for revaccination in field conditions.

The vector vaccine VECTORMUN HVT NDV provides reliable protection against NH and significantly reduces the spread of the virus in the environment. The vaccine does not cause adverse reactions and does not interact with other vaccines in the chicken respiratory tract, for example with a vaccine against infectious bronchitis of chickens. Repeated cycles of replication of the recombinant herpes-virus (HVT) stimulate long-term immunity against NH. The use of the HVT vector vaccine in the incubator completely addresses the problem of the interaction of the vaccine virus with maternal antibodies, as opposed to live and inactivated vaccines.

References

Calnek B. W. Diseases of Poultry // P. 1991-1231.

Avdosjeva I. K., Basarab O. B., Regenchuk V. V., Melnychuk I. L. Efektyvnist’ vaktsyny Vektormun proty njukaslskoji khvorooby brojleriv / Naukovo-tekhnichnyji bulletin DNDKI vetpreparativ. – 2016. ˗ vypusk 17, № 2. ˗ S. 174-180.

Published
2019-09-18
How to Cite
Avdosieva, I. K., Basarab, O. B., Reghenchuk, V. V., & Melnychuk, I. L. (2019). Effective innovations prevention newcastle disease. Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology, 20(2), 169-174. https://doi.org/10.36359/scivp.2019-20-2.22