The perspective of the use of subjects for prevention and treatment of bovine salmonelosis
The article presents the results of bacteriological monitoring of material from the age-old groups of eggs and meat crosses from 11 poultry farms for the presence of pathogens of bacterial infections in the period 2016-2018. The highest percentage of isolated crops during the last 3 years was: E. coli -72, 83.78 and Salmonella spp. 17,8,12 respectively. It was established that isolated field strains of salmonella from poultry with typing with specific salmonella serum from the Salmonella enteritidis, Salmonella typhimurium. Bacteriophage BAFASAL produced by Proteon Pharmaceuticals, Poland, containing a composition of the specific phages of Salmonella enteritidis and Salmonella typhimurium. caused lіsis of 97.8% of salmonella cultures.
Ukraine introduced the year 2027-2018. The feed supplement of Bafasal was used on egg crosses in 700 thousand heads of chickens and broilers 200 thousand heads. Proven effectiveness in the application of a dose of 1 liter per 50,000 head a day, for three weeks. The positive impact on the economic parameters of birds, as well as the conservation of birds, improved productivity and quality of meat, protection against salmonella, and a decrease in the number of feed programs have been established.
When applied, the bacteriophage is distributed predominantly in the intestine. In the absence of specific bacterial cells, after 20 hours, the bacteriophage is almost completely excreted from the body. In the presence of an organism susceptible to it, the culture of Salmonella sрp. there is an active lysis of bacterial cells and an increase in the concentration of bacteriophage, which causes the possibility of its practical application for the treatment of bird salmonellosis.
The aim of the work was to carry out bacteriological monitoring of pathological material from aged-age egg and meat crosses, the typing of isolated salmonella and to determine the lysis of isolated strains of salmonella to BAFASAL, containing the composition of the specific phages of Salmonella enteritidis and Salmonella typhimurium.
Atterbury R. J., Van Bergen M. A., Ortiz F., Lovell M. A., Harris J. A., De Boer A., Wagenaar J. A., Allen V. M., Barrow P. A. Bacteriophage therapy to reduce salmonella colonization of broiler chickens // Appl Environ Microbiol. ˗ 2007. ˗ 73: P. 4543-4549.
Grant A., Hashem F., Parveen S. Antimicrobial resistance and bacteriophage control in poultry // Sood Microbiol. ˗ 2016. ˗ 53. ˗ Р. 104-109.
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