THERAPY OF POULTRY WITH ORNITHOBACTERIOSIS
Ornithobacteriosis, caused by Ornithobacterium rhinotracheale, belongs to the group of respiratory diseases that are currently one of the main problems in industrial poultry, as it leads to significant economic losses due to reduced productivity in commercial and reproductive herds, poor egg production, as well as reducing growth and increasing the death and culling of poultry, high treatment costs. Diagnosis of infections caused by Ornithobacterium rhinotracheale is often difficult because clinical symptoms and postmortem changes are not specific and can be easily confused with those of other infections. The difficulty also lies in the fact that Ornithobacterium rhino-tracheale can be isolated by bacteriological method only in the early stages of the disease. For effective prevention and treatment of ORT use veterinary medicines (VM), namely: tetracyclines; macrolides - tilmicosin, thiamulin; new generation macrolide – eulosin; semi-synthetic penicillin amoxicillin, amoxiclav; germacap - a mixture of aqueous solutions of citrates of zinc, germanium, silver, made on the basis of modern nanotechnology. In Ukraine, there are 29 names of VM for the treatment of poultry against ORT, consisting of one-, 2 and 3 components, namely: doxycycline hyclate, sarafloxacin hydrochloride, tiamulin, tylvalosin, tilmicosin, fluoropheniol; tilmicosin + bromhexine hydrochloride and gentamicin + fluorophenicol+ doxycycline. .Enzyme-linked immunosorbent assay (ELISA) is used to control the presence of ornithobacteriosis in poultry. The presence of antibodies to this pathogen in many species of poultry indicates its wide circulation. A total of 82 batches of broilers and 43 batches of laying hens were tested for ELT serum in ELISA. Positive average titers of antibodies to ORT were detected among meat crosses of 24 batches, which is 29.3%, and egg crosses of 35 batches, which is 81.4%, which indicates a wide circulation of ornithobacteria among poultry. When using Eulosin 625 mg / g at a dose of 25 mg / kg orally with water for 5 days for the treatment of ORT broilers found: high therapeutic effect of the medicine – 82 %, increase in average daily gain - by 2.7%, preservation - by 1.4%; and the efficiency index improved by 5.4 %. To successfully control ORT, it is necessary to carry out a set of veterinary and sanitary measures, as well as constant serological monitoring of blood sera from different age groups of poultry and turkeys in ELISA for specific antibodies, indicating its circulation, in order to conduct timely effective antibiotic therapy.
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