Diagnosis of canine acute destructive pancreatitis

  • A. G. Milastnaia National University of Life and Environmental Sciences of Ukraine, Kyiv, Ukraine
  • V. B. Dukhnickiy National University of Life and Environmental Sciences of Ukraine, Kyiv, Ukraine
Keywords: acute destructive pancreatitis, pancreas, diagnosis, dogs, intoxication indexes, ultrasound research, doppler, leukogram

Abstract

The research describes the clinical, laboratory and instrumental examination of dogs with acute destructive pancreatitis. The main clinical signs of acute destructive pancreatitis dog are intense pain, frequent bouts of vomiting, abdominal distention. Leukocyte intoxication indexes of the dogs with acute destructive pancreatitis was characterised by increasing nuclear index – in 2,4 times, the index of rate sedimentation is 6,6 times, reactive responses of neutrophils – in 3 times, compared with in healthy animals. In the blood serum of dogs with acute destructive pancreatitis, increased content of urea and creatinine respectively in 3 and 2,7 times, increased the activity of amylase and lipase – 4 times in 3 times, aspartic and alaninaminotransferases action respectively in 2,7 and 2,4 times, g-glutamyltranspeptidase in 2,4 times, alkaline phosphatase – in 1,7 times compared with the indexes of healthy animals. Canine acute destructive pancreatitis accompanied the intensification of processes of lipids peroxide oxidation, which indicates a fair increase in the blood concentration of malonic dialdehyde and diene conjugates on 8 and 15 %, decreased activity catalase and superoxide dismutase on 19 and 17 % compared of healthy animals indexes. Ultrasound research of dogs with acute destructive pancreatitis, increasing the size of the pancreas, decrease echogenicity, blurred its contours and the availability of free fluid in the abdomen; study in B-mode visceral branches of the abdominal aorta is the deformation of the contour of the vessel wall and growth 10 % index of resistance of the main vessels, and, on the contrary, its reduction in the small arteries of the pancreas; pulse-wave Doppler increase averages Vps and IR in the period from 1 to 6 days, as well as an increase in Ved in the a. hepatica and a. linealis in the same period.

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Published
2019-09-18
How to Cite
Milastnaia, A. G., & Dukhnickiy, V. B. (2019). Diagnosis of canine acute destructive pancreatitis. Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology, 20(2), 104-112. https://doi.org/10.36359/scivp.2019-20-2.14