COMPARATIVE EVALUATION OF COMPLEX DRUGS BASED ON PIRANTEL PAMOAT, FEBANTEL AND PRAZIKVANTEL FOR HELMINTHOSIS OF DOGS AND CATS
The article presents data on the effectiveness of the new complex antiparasitic drug «Animal VetLine DeVorm plus anthelmintic drug for dogs and cats (suspension)» in comparison with the reference drugs «Drontal@ plus with meat taste» and «Drontal@ for cats» in use for therapeutic and prophylactic purposes in helminthiasis of dogs and cats of different breeds.
According to the results of helminthocoprological studies of feces, it was found that on the 7th day after the use of the experimental drug «Animal VetLine DeVorm plus anthelmintic for dogs and cats (suspension)» in one dog and one puppy (from 6 animals) a slight invasion (intensity of invasion of the pathogen Toxocara canis was 1–2 eggs in 1 g of feces) was observed, ie during this invasion the studied drug «Animal VetLine DeVorm plus anthelmintic for dogs and cats (suspension)» on the 7th day after application showed 83.3 % efficiency. However, the experimental animals had no invasion in the helminthocoprologic studies of the pathogen Toxocara canis on 14th day after treatment with this drug. In comparison, animals treated with reference drugs of endoparasitic pathogens on the 7th and 14th day of the study was not detected.
It should be noted that in cats on the 7th day after treatment, according to helminthocoprological studies, nematode pathogens were not detected.
The extensitivity of the experimental drug and reference drugs in field (production) trials for nematodes (Toxocara canis, Toxascaris leonina, Uncinaria stenocephala, Trichuris vulpis ) of puppies, dogs and cats was 100 %.
It was found that the tolerability of the antiparasitic drug by animals was good, it did not change the clinical signs and did not cause toxic effects. The drug has shown high extensibility in endoparasitic diseases of dogs and cats when used individually for therapeutic and prophylactic purposes and can be recommended for use in the practice of veterinary medicine.
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